Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 13/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | BCR | P11274 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554838 | 0.88 | MLNR (0.52) | MLNRMCHR1HIF1AEPAS1 | |
| SCHEMBL2767425 | 0.82 | MLNR (0.48) | MLNRMCHR1KCNH2 | |
| SCHEMBL2768358 | 0.80 | MLNR (0.64) | MLNRHIF1AEPAS1KCNH2 | |
| SCHEMBL2765835 | 0.79 | MLNR (0.72) | MLNR | |
| SCHEMBL2766394 | 0.79 | MLNR (0.53) | MLNRHIF1AEPAS1 | |
| SCHEMBL2767430 | 0.78 | MCHR1 (0.42) | MLNRMCHR1ABL1BCRHIF1A | |
| SCHEMBL13404794 | 0.73 | MLNR (0.49) | MLNRHIF1AEPAS1 | |
| SCHEMBL2767564 | 0.73 | MLNR (0.73) | MLNR | |
| SCHEMBL2765987 | 0.73 | MLNR (0.73) | MLNR | |
| SCHEMBL377692 | 0.72 | PKM (0.41) | HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041093-B1 | PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES | GLAXO GROUP LTD (GB) | 2010-04-21 | — | — | EP | disclosed |