Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655238 | 0.90 | GRM2 (0.39) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL2905268 | 0.89 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL27675253 | 0.88 | TP53 (0.35) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL2907956 | 0.88 | PDE4A (0.45) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL27655289 | 0.86 | GRM2 (0.40) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL2910468 | 0.81 | PDE4D (0.44) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL2902489 | 0.81 | PDE4D (0.44) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL4193004 | 0.81 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL4194617 | 0.79 | PDE4A (0.55) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL2910715 | 0.79 | GRM2 (0.41) | PDE4APDE4DPDE4BPDE4CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922144-A | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs | MEMORY PHARM CORP (US) | 2007-02-28 | — | — | CN | disclosed |