Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655238 | 0.90 | GRM2 (0.39) | TP53MAPTGRM2ALDH1A1USP2 | |
| SCHEMBL2908377 | 0.89 | LTC4S (0.42) | TP53MAPTGRM2SLC2A1FFAR4 | |
| SCHEMBL27675159 | 0.88 | PDE4A (0.43) | TP53MAPTGRM2ALDH1A1L3MBTL1 | |
| SCHEMBL27655289 | 0.86 | GRM2 (0.40) | TP53MAPTGRM2ALDH1A1USP2 | |
| SCHEMBL27675346 | 0.84 | CNR2 (0.34) | GRM2SLC2A1ALDH1A1L3MBTL1CNR2 | |
| SCHEMBL2910236 | 0.79 | PDE4D (0.46) | GRM2CNR2PDE4APDE4BPDE4C | |
| SCHEMBL8284806 | 0.79 | GRM2 (0.39) | GRM2CNR2 | |
| SCHEMBL2908741 | 0.78 | GRM2 (0.44) | TP53MAPTGRM2ALDH1A1USP2 | |
| SCHEMBL2910346 | 0.78 | GRM2 (0.45) | TP53MAPTGRM2ALDH1A1USP2 | |
| SCHEMBL2907956 | 0.77 | PDE4A (0.45) | TP53MAPTGRM2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922144-A | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs | MEMORY PHARM CORP (US) | 2007-02-28 | — | — | CN | disclosed |