Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767030 | 1.00 | LMNA (0.41) | LMNAPOLBHTR7TP53KCNK3 | |
| SCHEMBL2766198 | 0.92 | LMNA (0.42) | LMNAPOLBTP53MAPT | |
| SCHEMBL2765602 | 0.92 | LMNA (0.42) | LMNAPOLBTP53MAPT | |
| SCHEMBL2768238 | 0.92 | LMNA (0.42) | LMNAPOLBTP53MAPT | |
| SCHEMBL2765621 | 0.90 | LMNA (0.41) | LMNAPOLBTP53 | |
| SCHEMBL2766628 | 0.90 | LMNA (0.41) | LMNAPOLBTP53 | |
| SCHEMBL2766953 | 0.90 | LMNA (0.41) | LMNAPOLBTP53MAPT | |
| SCHEMBL2765232 | 0.90 | POLB (0.43) | LMNAPOLBTP53MAPT | |
| SCHEMBL2766127 | 0.90 | LMNA (0.43) | LMNAPOLBTP53MAPT | |
| SCHEMBL3287412 | 0.89 | TP53 (0.42) | LMNAPOLBHTR7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858890-B1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2010-04-14 | — | — | EP | disclosed |