Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747108 | 0.80 | GNAI3 (0.43) | ALDH1A1HRH3CHRM3ITGB3ITGA2B | |
| SCHEMBL7860170 | 0.80 | GFER (0.39) | GFERSMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15142807 | 0.80 | SMN1; SMN2 (0.45) | GFERSMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15142809 | 0.80 | SMN1; SMN2 (0.45) | GFERSMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2607208 | 0.80 | SMN1; SMN2 (0.45) | GFERSMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL12369696 | 0.79 | CHRM2 (0.39) | GFERSMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL12449636 | 0.79 | CHRM2 (0.39) | GFERSMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1682650 | 0.79 | GRM2 (0.43) | SMN1; SMN2LMNACYP2C19HSD17B10CYP2D6 | |
| SCHEMBL12449638 | 0.79 | CHRM2 (0.39) | GFERSMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19814985 | 0.79 | GRM2 (0.40) | SMN1; SMN2LMNACYP2C19HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1934082-A | Organic compounds | SPEEDEL EXPERIMENTA AG (CH) | 2007-03-21 | — | — | CN | disclosed |