Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 5/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629643 | 0.85 | NR3C2 (0.39) | NR3C2TRPV4PDE10AHSP90AA1ALDH1A1 | |
| SCHEMBL1219165 | 0.85 | HSP90AA1 (0.40) | NR3C2TRPV4PDE10AHSP90AA1ALDH1A1 | |
| SCHEMBL12722754 | 0.82 | PDE10A (0.49) | TRPV4PDE10AALDH1A1LMNAMAPT | |
| SCHEMBL27743220 | 0.80 | NR3C2 (0.42) | NR3C2PDE10AHSP90AA1ALDH1A1HSD17B10 | |
| SCHEMBL27763829 | 0.80 | NR3C2 (0.43) | NR3C2HSP90AA1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL1628788 | 0.78 | HSP90AA1 (0.41) | NR3C2PDE10AHSP90AA1ALDH1A1LMNA | |
| SCHEMBL1629805 | 0.77 | NR3C2 (0.41) | NR3C2HSP90AA1ALDH1A1LMNATP53 | |
| SCHEMBL1630418 | 0.76 | HSP90AA1 (0.41) | NR3C2PDE10AHSP90AA1ALDH1A1LMNA | |
| SCHEMBL1630525 | 0.75 | HSP90AA1 (0.44) | NR3C2PDE10AHSP90AA1HTTALDH1A1 | |
| SCHEMBL1628808 | 0.75 | ALDH1A1 (0.42) | NR3C2HSP90AA1HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006061-A | 1,5-diphenylpyrazoles | MERCK PATENT GMBH (DE) | 2007-07-25 | — | — | CN | disclosed |