Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GALR2 | O43603 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL952570 | 0.76 | ALDH1A1 (0.38) | ALDH1A1GAAL3MBTL1MAPTCRHBP | |
| SCHEMBL25341053 | 0.76 | MAPT (0.34) | ALDH1A1GAAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL3487176 | 0.75 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL20657212 | 0.73 | ALDH1A1 (0.43) | ALDH1A1GAAL3MBTL1MAPTCRHBP | |
| SCHEMBL2616395 | 0.73 | SMN1; SMN2 (0.37) | ALDH1A1GAAL3MBTL1MAPTKDM4E | |
| SCHEMBL2123641 | 0.72 | GAA (0.34) | ALDH1A1GAAMAPTCRHBPCRHR2 | |
| SCHEMBL3470550 | 0.72 | MAPT (0.34) | ALDH1A1GAAL3MBTL1MAPTCRHBP | |
| SCHEMBL15864377 | 0.71 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL25345518 | 0.70 | ALDH1A1 (0.39) | ALDH1A1GAAL3MBTL1MAPTKDM4E | |
| SCHEMBL20517661 | 0.70 | ALDH1A1 (0.43) | ALDH1A1GAAL3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1933834-A | Use of indazolecarboxamide derivatives for the preparation of a medicament for the treatment and prevention of malaria | SANOFI AVENTIS (FR) | 2007-03-21 | — | — | CN | disclosed |