Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676736 | 0.79 | MEN1 (0.42) | HTR2AHTR2CHTR2B | |
| SCHEMBL10675977 | 0.79 | MEN1 (0.42) | HTR2AHTR2CHTR2B | |
| SCHEMBL10676739 | 0.79 | MEN1 (0.42) | HTR2AHTR2CHTR2B | |
| SCHEMBL6406073 | 0.79 | MEN1 (0.42) | HTR2AHTR2CHTR2B | |
| SCHEMBL10675972 | 0.79 | MEN1 (0.42) | HTR2AHTR2CHTR2B | |
| SCHEMBL27483145 | 0.77 | HTR2A (0.44) | GRIA4HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL10123338 | 0.76 | HTR2C (0.45) | HTR2CHDAC8HDAC6HDAC1 | |
| SCHEMBL3554788 | 0.74 | HDAC8 (0.50) | GRIA4HDAC8HDAC6HDAC1 | |
| SCHEMBL21668620 | 0.72 | SLC6A3 (0.48) | GRIA4HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL25332827 | 0.72 | HDAC8 (0.51) | HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1890238-A | Hydronopol derivatives as agonists on human ORL1 receptors | SOLVAY PHARM GMBH (DE) | 2007-01-03 | — | — | CN | disclosed |