Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694192 | 0.88 | MEN1 (0.50) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL17542431 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL12735949 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL4678826 | 0.85 | GRIN2B (0.52) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL148277 | 0.85 | SCN5A (0.50) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL543032 | 0.85 | KMT2A (0.48) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL542683 | 0.85 | MEN1 (0.58) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL542709 | 0.85 | GRIN2B (0.52) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL3889285 | 0.84 | MEN1 (0.66) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL17272 | 0.84 | MEN1 (0.66) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |