Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NQO1 | P15559 | 4/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768360 | 0.84 | MAPT (0.35) | MAPTNQO1KMT2AKDM4EMEN1 | |
| SCHEMBL27579712 | 0.84 | MAPT (0.35) | MAPTNQO1KMT2AKDM4EMEN1 | |
| SCHEMBL28815404 | 0.84 | MAPT (0.35) | MAPTNQO1KMT2AKDM4EMEN1 | |
| SCHEMBL28758750 | 0.81 | CA1 (0.38) | MAPTNQO1CDK4CCND1KMT2A | |
| SCHEMBL28781324 | 0.80 | ALDH1A1 (0.36) | MAPTNQO1CDK4CCND1KMT2A | |
| SCHEMBL27409389 | 0.74 | NQO1 (0.43) | MAPTNQO1CDK4CCND1KMT2A | |
| SCHEMBL27369368 | 0.74 | CA1 (0.39) | MAPTNQO1CDK4CCND1KMT2A | |
| SCHEMBL27267954 | 0.73 | CA1 (0.43) | MAPTNQO1CDK4CCND1KDM4E | |
| Ether SCHEMBL28248062 | 0.72 | NQO1 (0.38) | MAPTNQO1KMT2AKDM4EALDH1A1 | |
| Furan SCHEMBL28228820 | 0.71 | NQO1 (0.38) | MAPTNQO1CDK4CCND1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100508941-C | Beta-substituted tetrahydropyrans (ketones), method for the synthesis thereof and use thereof | MANE FILS V (FR) | 2009-07-08 | — | — | CN | disclosed |
| CN-101001605-A | Beta-substituted tetrahydropyran(on)s and method for the synthesis and the use thereof | MANE FILS V (FR) | 2007-07-18 | — | — | CN | disclosed |