SCHEMBL27675773

SCHEMBL27675773

O=[N+]([O-])c1ccc(Oc2ccccc2)c(C(F)(F)F)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 1/20 0.53
MAPT P10636 6/20 0.50
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
LMNA P02545 4/20 0.50
HSPB1 P04792 3/20 0.50
CYP19A1 P11511 2/20 0.50
MAPK1 P28482 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MLNR O43193 1/20 0.50
MMP1 P03956 1/20 0.50
MPO P05164 1/20 0.50
GLA P06280 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8141281 0.92 HSPB1 (0.57) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL27782641 0.91 EPAS1 (0.54) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL31457196 0.91 HSPB1 (0.57) CYP1A2CYP2C9CYP2C19MAPTMEN1
Water SCHEMBL28087112 0.90 EPAS1 (0.53) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL29519502 0.89 CYP1A2 (0.56) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL4780615 0.88 HSPB1 (0.54) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL9171793 0.88 CYP1A2 (0.64) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL11212598 0.86 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL10880653 0.86 HSPB1 (0.51) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL1148931 0.86 HSPB1 (0.51) CYP1A2CYP2C9CYP2C19MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327278-A Trifluoromethyl-terminated fluorinated polyamide imide polymer, preparation method thereof and application thereof in electrochromic film 南通际光光电科技有限公司 2024-01-02 CN claimed
CN-117327280-A Fluorine-containing linear long-chain transparent polyamide imide polymer, preparation method thereof and application thereof in optical transparent film 南通际光光电科技有限公司 2024-01-02 CN claimed
CN-117263805-A Preparation method of 1, 4-bis (4-nitro-2-trifluoromethyl phenoxy) benzene 天津众泰材料科技有限公司 2023-12-22 CN claimed
CN-116987541-A High-speed low-temperature bearing lubricating grease and preparation method thereof 安徽和欣润滑科技有限公司 2023-11-03 CN claimed
CN-109456482-B Fluorine-containing polyimide polymer, preparation method and polyimide composite film 湖南工学院 2020-05-12 CN claimed
CN-101560166-B Method for preparing 1,3-di(2-trifluoromethyl-4-aminophenoxy) benzene UNIV DONGHUA 2013-01-02 CN claimed
CN-101580474-B Preparation method of 1,4-bis(2-trifluoromethyl-4-aminophenoxyl)benzene UNIV DONGHUA 2012-07-18 CN claimed
CN-101560156-B Preparation method of 1,3-bi(2-trifluoromethyl-4-nitrophenoxyl)benzene UNIV DONGHUA 2012-07-18 CN claimed
CN-101580474-A Preparation method of 1,4-bis(2-trifluoromethyl-4-aminophenoxyl)benzene UNIV DONGHUA (CN) 2009-11-18 CN claimed
CN-101560166-A Method for preparing 1,3-di(2-trifluoromethyl-4-aminophenoxy) benzene UNIV DONGHUA (CN) 2009-10-21 CN claimed
CN-101560156-A Preparation method of 1,3-bi(2-trifluoromethyl-4-nitrophenoxyl)benzene UNIV DONGHUA (CN) 2009-10-21 CN claimed
CN-101550084-A Preparation method of 1-4-bi-(2-trifluoromethyl-4-nitrophenoxy)benzene UNIV DONGHUA (CN) 2009-10-07 CN claimed
CN-100540527-C A kind of triamido monomer and synthetic method thereof and application UNIV JILIN (CN) 2009-09-16 CN claimed
CN-100999476-A Triamido monomer and its synthesizing process and use UNIV JILIN (CN) 2007-07-18 CN claimed
CN-117327278-A Trifluoromethyl-terminated fluorinated polyamide imide polymer, preparation method thereof and application thereof in electrochromic film 南通际光光电科技有限公司 2024-01-02 CN disclosed
CN-117327280-A Fluorine-containing linear long-chain transparent polyamide imide polymer, preparation method thereof and application thereof in optical transparent film 南通际光光电科技有限公司 2024-01-02 CN disclosed
CN-117263805-A Preparation method of 1, 4-bis (4-nitro-2-trifluoromethyl phenoxy) benzene 天津众泰材料科技有限公司 2023-12-22 CN disclosed
CN-101503360-A Preparation of 2- tertiary butyl-1,4-bis (4-nitro-2-trifluoromethyl phenoxy) benzene UNIV DONGHUA (CN) 2009-08-12 CN disclosed
CN-101503360-A Preparation of 2- tertiary butyl-1,4-bis (4-nitro-2-trifluoromethyl phenoxy) benzene UNIV DONGHUA (CN) 2009-08-12 CN disclosed
CN-100999476-A Triamido monomer and its synthesizing process and use UNIV JILIN (CN) 2007-07-18 CN disclosed