Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380975 | 0.89 | KMO (0.56) | KMOPTPN1AXL | |
| SCHEMBL28375588 | 0.87 | KDM4E (0.46) | KMOKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28759853 | 0.82 | MEN1 (0.47) | KMOP2RY14KDM4EALDH1A1MEN1 | |
| SCHEMBL2589690 | 0.81 | MCL1 (0.56) | KMOP2RY14KDM4EALDH1A1MEN1 | |
| SCHEMBL10988314 | 0.81 | MEN1 (0.59) | KMOP2RY14KDM4EALDH1A1MEN1 | |
| SCHEMBL28376135 | 0.80 | HDAC8 (0.50) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL18546013 | 0.78 | AKR1C3 (0.49) | P2RY14MEN1KMT2A | |
| SCHEMBL10900757 | 0.78 | GRIN2D (0.53) | KMOP2RY14KDM4EALDH1A1HPGD | |
| SCHEMBL27880686 | 0.78 | MAP4K4 (0.50) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL12863273 | 0.76 | CYP11B1 (0.49) | KMOKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1938016-A | Use of benzonaphthoazulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders | GLAXOSMITHKLINE ZAGREB (HR) | 2007-03-28 | — | — | CN | claimed |
| CN-1938016-A | Use of benzonaphthoazulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders | GLAXOSMITHKLINE ZAGREB (HR) | 2007-03-28 | — | — | CN | disclosed |