Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337333 | 0.95 | ASIC3 (0.79) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL21925686 | 0.86 | ASIC3 (0.56) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL28593789 | 0.85 | ASIC3 (0.66) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL21055972 | 0.85 | ASIC3 (0.66) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL12692399 | 0.85 | ASIC3 (0.66) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL12436465 | 0.85 | ASIC3 (0.92) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL30437053 | 0.85 | ASIC3 (0.66) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL3788626 | 0.84 | ASIC3 (1.00) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL18745790 | 0.84 | ASIC3 (0.70) | ASIC3KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL28427582 | 0.84 | ASIC3 (0.53) | ASIC3KMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100360507-C | Inhibition of raf kinase using substituted heterocyclic ureas | BAYER AG (US) | 2008-01-09 | — | — | CN | disclosed |