Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742966 | 0.84 | CNR1 (0.61) | CNR1CNR2L3MBTL1TLR7ALOX5 | |
| SCHEMBL27702044 | 0.83 | CNR2 (0.46) | CNR1CNR2L3MBTL1TLR7ALOX5 | |
| SCHEMBL19102048 | 0.81 | DDX3X (0.41) | CNR1CNR2TLR7ALOX5CYP1A2 | |
| SCHEMBL27854790 | 0.78 | HTT (0.47) | CNR1CNR2TLR7ALOX5CYP1A2 | |
| SCHEMBL27854802 | 0.78 | TLR7 (0.39) | CNR1CNR2TLR7ALOX5CYP1A2 | |
| SCHEMBL4054662 | 0.78 | CNR1 (0.45) | CNR1CNR2L3MBTL1TLR7ALOX5 | |
| SCHEMBL27836801 | 0.78 | CNR2 (0.45) | CNR1CNR2TDP1ALOX5NPC1 | |
| SCHEMBL27836991 | 0.77 | TLR7 (0.44) | CNR1CNR2TDP1L3MBTL1TLR7 | |
| SCHEMBL27938671 | 0.77 | CNR1 (0.44) | CNR1CNR2TLR7MAPK1RAB9A | |
| SCHEMBL2364213 | 0.77 | NPC1 (0.53) | CNR1CNR2L3MBTL1TLR7ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026985-A | Quinazoline derivatives as RAF kinase modulators and methods and uses thereof | AMBIT BIOSCIENCES CORPORATON | 2011-04-20 | — | — | CN | disclosed |
| CN-101006087-B | Triazolopyridinylsulfanyl derivatives as p38 MAP kinase inhibitors | PFIZER | 2010-09-29 | — | — | CN | disclosed |
| CN-101316841-A | Arylmethylene urea derivative and use thereof | TORAY INDUSTRIES (JP) | 2008-12-03 | — | — | CN | disclosed |
| CN-101006087-A | Triazolopyridinylsulfanyl derivatives as p38 MAP kinase inhibitors | PFIZER (US) | 2007-07-25 | — | — | CN | disclosed |