SCHEMBL2767697

SCHEMBL2767697

NC1(N)CC(O)=CC=C1c1ccc(O)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.37
ESR2 Q92731 3/20 0.37
KDM1A O60341 1/20 0.32
MMP3 P08254 1/20 0.32
BCL2L1 Q07817 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
NPC1 O15118 2/20 0.31
MAPT P10636 2/20 0.31
NFKB1 P19838 2/20 0.31
RAB9A P51151 2/20 0.31
USP2 O75604 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
ABL1 P00519 1/20 0.31
ABCB1 P08183 1/20 0.31
BCR P11274 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7122797 0.77 SMN1; SMN2 (0.39) ESR1ESR2MMP3BCL2L1SMN1; SMN2
SCHEMBL8735556 0.77 ESR1 (0.37) ESR1ESR2MMP3BCL2L1SMN1; SMN2
SCHEMBL28653409 0.73 MEN1 (0.34) ESR1ESR2MMP3BCL2L1MEN1
SCHEMBL6539105 0.65 SMN1; SMN2 (0.39) ESR1ESR2KDM1AMMP3BCL2L1
SCHEMBL13859776 0.60 ESR1 (0.46) ESR1ESR2MMP3BCL2L1SMN1; SMN2
Hydrazine SCHEMBL29067366 0.60 ESR1 (0.85) ESR1ESR2KDM1AMMP3BCL2L1
SCHEMBL15632 0.59 ESR1 (1.00) ESR1ESR2MMP3BCL2L1SMN1; SMN2
SCHEMBL9090705 0.59 ESR1 (1.00) ESR1ESR2MMP3BCL2L1SMN1; SMN2
SCHEMBL6292004 0.59 ESR1 (1.00) ESR1ESR2MMP3BCL2L1SMN1; SMN2
Hydroquinone SCHEMBL5712110 0.59 ESR1 (1.00) ESR1ESR2MMP3BCL2L1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781541-B2 Polyimide silicone resin and thermosetting composition comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-24 US claimed
EP-1842870-B1 Polymide silicone resin and thermosetting composition comprising the same SHINETSU CHEMICAL CO (JP) 2014-05-21 EP disclosed
EP-1642919-B1 Polyimide having an alcoholic hydroxyl group and a process for the preparation thereof SHINETSU CHEMICAL CO (JP) 2012-07-18 EP disclosed
US-7781541-B2 Polyimide silicone resin and thermosetting composition comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-24 US disclosed
EP-1705204-B1 Photosensitive resin and a method of preparing the same SHINETSU CHEMICAL CO (JP) 2010-04-21 EP disclosed
US-7678874-B2 Polyimide having an alcoholic hydroxyl group and a process for the preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-03-16 US disclosed
US-20090131620-A1 POLYIMIDE HAVING AN ALCOHOLIC HYDROXYL GROUP AND A PROCESS FOR THE PREPARATION THEREOF SUGO MICHIHIRO 2009-05-21 US disclosed
EP-1842870-A2 Polymide silicone resin and thermosetting composition comprising the same Shin-Etsu Chemical Company, Ltd. (JP) 2007-10-10 EP disclosed
US-20070197680-A1 Polyimide silicone resin and thermosetting composition comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-08-23 US disclosed
EP-1705204-A1 Photosensitive resin and a method of preparing the same Shinetsu Chemical Co., Ltd. (JP) 2006-09-27 EP disclosed
US-20060183880-A1 Photosensitive resin and a method of preparing the same SHIN-ETSU CHENICAL CO., LTD. 2006-08-17 US disclosed
EP-1642919-A1 Polyimide having an alcoholic hydroxyl group and a process for the preparation thereof Shin-Etsu Chemical Co., Ltd. (JP) 2006-04-05 EP disclosed
US-20060069227-A1 Polyimide having an alcoholic hydroxyl group and a process for the preparation thereof SHIN-ETSU CHEMICAL CO., LTD. 2006-03-30 US disclosed