Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Resveratrol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 2/20 | 0.73 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.73 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.73 |
| ▸ | TTR | P02766 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | CA12 | O43570 | 3/20 | 0.73 |
| ▸ | CA1 | P00915 | 3/20 | 0.73 |
| ▸ | CA2 | P00918 | 3/20 | 0.73 |
| ▸ | CA3 | P07451 | 3/20 | 0.73 |
| ▸ | CA4 | P22748 | 3/20 | 0.73 |
| ▸ | CA6 | P23280 | 3/20 | 0.73 |
| ▸ | CA5A | P35218 | 3/20 | 0.73 |
| ▸ | CA7 | P43166 | 3/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resveratrol SCHEMBL28030055 | 0.98 | PTGS2 (0.76) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL21225662 | 0.98 | PTGS2 (0.76) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL29473334 | 0.98 | PTGS2 (0.76) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL29128880 | 0.92 | PTGS1 (0.79) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL28375834 | 0.90 | PTGS1 (0.76) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL28719858 | 0.90 | PTGS2 (0.83) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL27651471 | 0.88 | PTGS1 (0.95) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL27819599 | 0.88 | PTGS1 (0.95) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL22245438 | 0.87 | PTGS2 (0.66) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 | |
| Resveratrol SCHEMBL27883730 | 0.86 | PTGS2 (0.76) | PTGS2PTGS1KDM4ECYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101026959-A | Fungicidally active polymer dispersions and use thereof | CELANESE EMULSIONS GMBH (DE) | 2007-08-29 | — | — | CN | claimed |
| CN-101026959-B | Fungicidally active polymer dispersions and use thereof | CELANESE EMULSIONS GMBH | 2010-10-13 | — | — | CN | disclosed |
| CN-101026959-A | Fungicidally active polymer dispersions and use thereof | CELANESE EMULSIONS GMBH (DE) | 2007-08-29 | — | — | CN | disclosed |