Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677658 | 0.94 | PIK3CD (0.49) | USP30PIK3CDCNR1CNR2ADORA1 | |
| SCHEMBL27696246 | 0.88 | ALDH1A1 (0.49) | CNR1CNR2ADORA1BTKBRD4 | |
| SCHEMBL21598995 | 0.87 | CNR1 (0.47) | USP30PIK3CDANO1CNR1CNR2 | |
| SCHEMBL4221845 | 0.85 | JAK3 (0.42) | BTK | |
| SCHEMBL4218823 | 0.83 | P2RY12 (0.45) | USP30CNR1CNR2PIM1PIM2 | |
| SCHEMBL21750619 | 0.82 | PIK3CD (0.49) | USP30PIK3CDADORA1BTKBRD4 | |
| SCHEMBL31434311 | 0.82 | PIK3CD (0.49) | USP30PIK3CDADORA1BTKBRD4 | |
| SCHEMBL28767616 | 0.82 | PIK3CD (0.49) | USP30PIK3CDADORA1BTKBRD4 | |
| SCHEMBL27696270 | 0.82 | USP30 (0.48) | USP30PIK3CDANO1ADORA1BTK | |
| SCHEMBL21599034 | 0.81 | USP30 (0.47) | USP30PIK3CDANO1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001851-B | Hydroxyamide compounds having activity as inhibitors of histone deacetylase (HDAC) | ASTELLAS PHARMA INC | 2011-04-20 | — | — | CN | disclosed |
| CN-101001851-A | Hydroxyamide compounds having activity as inhibitors of histone deacetylase (HDAC) | ASTELLAS PHARMA INC (JP) | 2007-07-18 | — | — | CN | disclosed |