Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 4/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696376 | 0.79 | MAPT (0.37) | KMT2AMAPTKDM4ELMNANPSR1 | |
| SCHEMBL27678046 | 0.78 | KDM4E (0.37) | KMT2AMAPTKDM4ELMNANPSR1 | |
| SCHEMBL5022953 | 0.77 | KDM4E (0.53) | KMT2AMAPTKDM4ELMNANPSR1 | |
| SCHEMBL5023522 | 0.77 | ALDH1A1 (0.39) | KMT2AMAPTKDM4ENPSR1MEN1 | |
| SCHEMBL5016984 | 0.77 | MAPT (0.43) | KMT2AMAPTKDM4ELMNANPSR1 | |
| SCHEMBL5027363 | 0.75 | KDM4E (0.39) | KMT2AMAPTKDM4ELMNAMEN1 | |
| Benzene SCHEMBL5016963 | 0.74 | KMT2A (0.42) | KMT2AMAPTKDM4ELMNANPSR1 | |
| SCHEMBL5023088 | 0.73 | KMT2A (0.43) | KMT2AMAPTKDM4ELMNANPSR1 | |
| SCHEMBL5025793 | 0.72 | KDM4E (0.53) | KMT2AMAPTKDM4ELMNANPSR1 | |
| SCHEMBL5023519 | 0.72 | KDM4E (0.42) | KMT2AMAPTKDM4ELMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100368407-C | 2-aminobenzothiazoles as CB1 receptor inverse agonists | HOFFMANN LA ROCHE (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-100368407-C | 2-aminobenzothiazoles as CB1 receptor inverse agonists | HOFFMANN LA ROCHE (CH) | 2008-02-13 | — | — | CN | disclosed |