SCHEMBL27678501

SCHEMBL27678501

CCc1ccc(C=C/C=C/C=C/CO)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
TUBB1 Q9H4B7 1/20 0.44
APP P05067 4/20 0.42
LMNA P02545 4/20 0.41
KDM4E B2RXH2 3/20 0.41
KMT2A Q03164 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAOA P21397 3/20 0.39
MAOB P27338 2/20 0.38
CYP2C9 P11712 1/20 0.37
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18296917 0.98 ALOX5 (0.47) ALOX5PTGS1PTGS2TUBB1APP
SCHEMBL2837690 0.84 ALOX5 (0.52) ALOX5PTGS1PTGS2TUBB1LMNA
SCHEMBL2837688 0.84 ALOX5 (0.52) ALOX5PTGS1PTGS2TUBB1LMNA
SCHEMBL27738997 0.81 APP (0.45) ALOX5PTGS1PTGS2TUBB1APP
SCHEMBL18296919 0.79 ALOX5 (0.43) ALOX5PTGS1PTGS2TUBB1APP
SCHEMBL27832380 0.79 APP (0.39) ALOX5PTGS1APPKDM4EKMT2A
SCHEMBL10533955 0.79 CA1 (0.45) ALOX5PTGS1PTGS2TUBB1APP
SCHEMBL27319263 0.77 CYP3A4 (0.40) PTGS1PTGS2TUBB1APPALDH1A1
SCHEMBL27343740 0.76 KDM4E (0.47) PTGS1PTGS2APPLMNAKDM4E
SCHEMBL8948448 0.76 MAOB (0.61) ALOX5PTGS1PTGS2TUBB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209539-A Hinge polymer NOVA CHEM INT SA 2015-12-30 CN disclosed
CN-101654562-B Resin blend and molding product thereof TORAY FIBER RES INST CN CO LTD 2012-08-08 CN disclosed
CN-101392069-B Additive agent mixture and preparation method TORAY FIBER RES INST CN CO LTD 2012-01-18 CN disclosed
CN-101654562-A Resin blend and molding product thereof TORAY FIBER RES INST CN CO LTD 2010-02-24 CN disclosed
CN-101392069-A Additive agent mixture and preparation method TORAY FIBER RES INST CN CO LTD (CN) 2009-03-25 CN disclosed
CN-101265355-A Polylactic acid mixture and forming articles thereof TORAY FIBER RES INST CN CO LTD (CN) 2008-09-17 CN disclosed
CN-101027353-A Porous inorganic materials containing polymeric additives CIBA SC HOLDING AG (CH) 2007-08-29 CN disclosed