SCHEMBL27678902

SCHEMBL27678902

O=C(O)[C@@H]1C[C@@H](O)CN1O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.55
GAA P10253 1/20 0.34
MME P08473 1/20 0.33
ACE P12821 2/20 0.32
SCN9A Q15858 2/20 0.31
PIK3CD O00329 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11008405 0.79
SCHEMBL28153658 0.78 ATM (0.57) ATMGAAMMEACEPIK3CD
SCHEMBL28435063 0.74 MMP2 (0.39) ATM
SCHEMBL28435060 0.74 MMP2 (0.39) ATM
SCHEMBL689912 0.74 ATM (0.59) ATMGAAMMEACEPIK3CD
SCHEMBL6819605 0.74 ATM (0.53) ATMGAAMMEACESCN9A
SCHEMBL6678799 0.74 ATM (0.53) ATMGAAMMEACE
SCHEMBL6018134 0.74 ATM (0.53) ATMGAAMMEACE
SCHEMBL21621506 0.74 ATM (0.53) ATMGAAMMEACE
SCHEMBL18870966 0.74 ATM (0.53) ATMGAAMMEACESCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109937040-A METHODS OF TREATING LIVER DISEASE 吉利德科学公司 2019-06-25 CN disclosed
CN-105188727-A Whitening promoting agent or atopic dermatitis improving agent NITTA GELATIN KK 2015-12-23 CN disclosed
CN-100528127-C Nanometer skin-activating emulsion cosmetics and its preparation process NORTHWEST AGRICULTURAL & FORES (CN) 2009-08-19 CN disclosed
CN-1931122-A Nanometer skin-activating emulsion cosmetics and its prepn process NORTHWEST AGRICULTURAL & FORES (CN) 2007-03-21 CN disclosed