Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753609 | 0.91 | GRM1 (0.39) | MCHR1MAPTGRM1MDM2EGFR | |
| SCHEMBL1689350 | 0.85 | MAPT (0.43) | MCHR1MAPTGRM1ALDH1A1TSHR | |
| SCHEMBL1688934 | 0.85 | MAPT (0.45) | MCHR1MAPTGRM1ALDH1A1TSHR | |
| SCHEMBL1753421 | 0.84 | MCHR1 (0.42) | MCHR1MAPTGRM1ALDH1A1TSHR | |
| SCHEMBL27679298 | 0.83 | GRM1 (0.41) | MCHR1MAPTGRM1MDM2TP53 | |
| SCHEMBL1753437 | 0.83 | MCHR1 (0.46) | MCHR1MAPTGRM1ALDH1A1TSHR | |
| SCHEMBL1688952 | 0.82 | GABRA2 (0.41) | MAPTGRM1EGFRTP53IDO1 | |
| SCHEMBL1689334 | 0.81 | GRM1 (0.45) | MCHR1MAPTGRM1ALDH1A1TSHR | |
| SCHEMBL1753587 | 0.81 | MAPT (0.47) | MCHR1MAPTGRM1ALDH1A1TSHR | |
| SCHEMBL1688997 | 0.79 | TP53 (0.47) | MCHR1MAPTGRM1MDM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102241680-A | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC | 2011-11-16 | — | — | CN | claimed |
| CN-101048408-A | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC (BM) | 2007-10-03 | — | — | CN | claimed |
| CN-102241680-A | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC | 2011-11-16 | — | — | CN | disclosed |
| CN-101048408-B | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC | 2011-07-06 | — | — | CN | disclosed |
| CN-101048408-A | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC (BM) | 2007-10-03 | — | — | CN | disclosed |