Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824673 | 0.77 | LMNA (0.39) | NOTUMCYP2C9CYP2C19 | |
| SCHEMBL1149649 | 0.74 | DAO (0.42) | — | |
| SCHEMBL25047032 | 0.73 | CYP1A2 (0.48) | CYP2C9 | |
| SCHEMBL12858054 | 0.73 | DAO (0.44) | — | |
| SCHEMBL1149425 | 0.73 | DHODH (0.49) | — | |
| SCHEMBL28764496 | 0.71 | GRM1 (0.34) | NOTUM | |
| SCHEMBL1149198 | 0.71 | DAO (0.52) | CYP2D6CYP2C19 | |
| SCHEMBL1149646 | 0.70 | DAO (0.48) | — | |
| SCHEMBL27680344 | 0.68 | NOTUM (0.39) | NOTUMCYP2C19 | |
| SCHEMBL6111302 | 0.68 | HCAR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922149-A | Pyrrole and pyrazole daao inhibitors | SEPRACOR INC (US) | 2007-02-28 | — | — | CN | disclosed |