Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.67 |
| ▸ | DHODH | Q02127 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799444 | 0.85 | DHODH (0.71) | CHATDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL12417102 | 0.85 | DHODH (0.71) | CHATDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL5363618 | 0.85 | DHODH (0.71) | CHATDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL14037032 | 0.83 | ALDH1A1 (0.64) | CHATALDH1A1KDM4EHPGDGAA | |
| SCHEMBL30930803 | 0.83 | DHODH (0.63) | CHATDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL29015134 | 0.83 | DHODH (0.68) | CHATDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL11781801 | 0.82 | CHAT (0.61) | CHATDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL28903546 | 0.82 | CHAT (0.54) | CHATDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL14383575 | 0.80 | CHAT (0.63) | CHATDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL28320760 | 0.76 | DHODH (0.59) | CHATDHODHALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100335468-C | Diaryl amidine compound, its production, medicinal composition and use | DRUG INST CHINESE ACADEMY OF M (CN) | 2007-09-05 | — | — | CN | disclosed |