SCHEMBL27680461

SCHEMBL27680461

COc1cccc(PC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.52
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
ENPP2 Q13822 1/20 0.45
FBP1 P09467 1/20 0.44
CA4 P22748 1/20 0.44
CHRM5 P08912 1/20 0.44
IDO1 P14902 1/20 0.42
AGXT P21549 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8029394 0.84 ACHE (0.54) ACHECA1CA2CA7CA9
Hydrochloric Acid SCHEMBL28248413 0.82 ACHE (0.52) ACHECA1CA2CA7CA9
Hydrochloric Acid SCHEMBL2154395 0.82 ACHE (0.52) ACHECA1CA2CA7CA9
SCHEMBL18575649 0.78 CA4 (0.52) ACHECA1CA2CA7CA9
1,3-Dimethoxybenzene SCHEMBL9350 0.77 ACHE (0.70) ACHECA1CA2CA7CA9
SCHEMBL21041703 0.77 ACHE (0.35) ACHE
1,3-Dimethoxybenzene SCHEMBL901285 0.77 ACHE (0.70) ACHECA1CA2CA7CA9
Hydrochloric Acid SCHEMBL2155238 0.77 CA4 (0.50) ACHECA1CA2CA7CA9
SCHEMBL29242308 0.75 ACHE (0.45) ACHECA1CA2CA7CA9
1,3-Dimethoxybenzene SCHEMBL28343465 0.75 ACHE (0.67) ACHECA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101027278-A Preparation of beta-amino acids having affinity for the alpha-2-delta protein WARNER LAMBERT CO (US) 2007-08-29 CN disclosed