Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211804 | 0.86 | KMT2A (0.70) | KMT2AMAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL31532327 | 0.86 | KMT2A (0.70) | KMT2AMAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL1996711 | 0.84 | KMT2A (1.00) | KMT2AMAPK1RAB9APTGS1NPC1 | |
| SCHEMBL9779781 | 0.84 | KMT2A (0.68) | KMT2AMAPK1RAB9APTGS1NPC1 | |
| SCHEMBL27885019 | 0.84 | KMT2A (0.68) | KMT2AMAPK1ALDH1A1RAB9APTGS1 | |
| Hydrochloric Acid SCHEMBL9779782 | 0.84 | KMT2A (0.68) | KMT2AMAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL10328708 | 0.84 | KMT2A (0.68) | KMT2AMAPK1MEN1ALDH1A1RAB9A | |
| SCHEMBL709672 | 0.84 | KMT2A (0.68) | KMT2AMAPK1ALDH1A1RAB9APTGS1 | |
| SCHEMBL16023928 | 0.83 | KMT2A (0.57) | KMT2AMAPK1ALDH1A1PTGS1CES2 | |
| Hydrazine SCHEMBL28254112 | 0.82 | KMT2A (0.71) | KMT2AMAPK1ALDH1A1RAB9APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048405-A | Aryl-substituted piperazine derivatives | NEUROGEN CORP (US) | 2007-10-03 | — | — | CN | disclosed |