Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680503 | 0.84 | KMT2A (0.72) | KMT2AMAPK1KDM4EPOLBGAA | |
| SCHEMBL31532327 | 0.82 | KMT2A (0.70) | KMT2ASMN1; SMN2MAPK1KDM4ENPC1 | |
| SCHEMBL9906446 | 0.82 | KMT2A (0.46) | KMT2AMAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL211804 | 0.82 | KMT2A (0.70) | KMT2ASMN1; SMN2MAPK1KDM4ENPC1 | |
| SCHEMBL24198737 | 0.81 | KMT2A (0.64) | KMT2AMAPTSMN1; SMN2MAPK1KDM4E | |
| SCHEMBL9779781 | 0.81 | KMT2A (0.68) | KMT2AMAPK1KDM4ELMNAPTGS1 | |
| SCHEMBL27885019 | 0.81 | KMT2A (0.68) | KMT2AMAPTMAPK1KDM4EPOLB | |
| SCHEMBL10328708 | 0.81 | KMT2A (0.68) | KMT2AMAPK1KDM4EPOLBGAA | |
| Hydrochloric Acid SCHEMBL9779782 | 0.81 | KMT2A (0.68) | KMT2ASMN1; SMN2MAPK1KDM4ENPC1 | |
| SCHEMBL1996711 | 0.81 | KMT2A (1.00) | KMT2ASMN1; SMN2MAPK1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705296-A1 | HETEROARYLINDOLE INHIBITORS OF APOL-1 | OmniAB, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4688785-A1 | 5-AMINO-6, 8-DIHYDRO-1H-FURO [3, 4-D] PYRROLO [3, 2-B] PYRIDINE-2-CARBOXAMIDE DERIVATIVES AS MTA-COOPERATIVE INHIBITORS OF PRMT5 | Beone Medicines I GmbH (CH) | 2026-02-11 | — | — | EP | disclosed |
| US-20250388585-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4638436-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4251624-B1 | TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS | AMGEN INC (US) | 2025-10-29 | — | — | EP | disclosed |
| US-12448388-B2 | PRMT5 inhibitors and uses thereof | GILEAD SCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| EP-4598923-A1 | SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS | The Regents of the University of California (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20250136594-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-01 | — | — | US | disclosed |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2025-01-30 | — | — | US | disclosed |
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-101611037-A | Pyridyl-triazolopyrimidine derivative or its salt, the sterilant that comprises it and its preparation method | ISHIHARA SANGYO KAISHA (JP) | 2009-12-23 | — | — | CN | disclosed |
| EP-2118113-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099902-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-08-21 | — | — | WO | disclosed |
| US-20070043011-A1 | Substituted benzanilide compound and noxious organism controlling agent | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1671941-A1 | SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2006-06-21 | — | — | EP | disclosed |
| CN-1114593-C | Preparation of 2-substituted pyridines | DOW AGRICULTURAL IMPROVING INC (US) | 2003-07-16 | — | — | CN | disclosed |
| EP-0955291-B1 | Preparation of 2-substituted pyridines | DOW AGROSCIENCES LLC (US) | 2002-07-10 | — | — | EP | disclosed |
| US-6054583-A | Preparation of 2-substituted pyridines | ROHM AND HAAS COMPANY (US) | 2000-04-25 | — | — | US | disclosed |
| CN-1238331-A | Preparation of 2-substituted pyridines | ROHM & HAAS (US) | 1999-12-15 | — | — | CN | disclosed |
| EP-0955291-A1 | Preparation of 2-substituted pyridines | ROHM AND HAAS COMPANY (US) | 1999-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388585-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT1, PRMT5, PRMT6 | KMT2A 67/4885MAPT 3947/4885SMN1; SMN2 1498/4885 |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | GBA1, GAA, GBA2 | KMT2A 3498/4885MAPT 578/4885SMN1; SMN2 159/4885 |
| US-20250136594-A1 | COMPOUNDS AND METHODS OF USE | CNKSR1, UGT1A1, REV1 | KMT2A 2276/4885MAPT 3881/4885SMN1; SMN2 1886/4885 |
| US-12448388-B2 | PRMT5 inhibitors and uses thereof | PRMT5, PRMT1, PRMT9 | KMT2A 52/4885MAPT 2217/4885SMN1; SMN2 1278/4885 |
| US-20070043011-A1 | Substituted benzanilide compound and noxious organism controlling agent | L3MBTL1, L3MBTL3, L3MBTL4 | KMT2A 2055/4885MAPT 4655/4885SMN1; SMN2 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.