Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359215 | 0.82 | CYP4F2 (0.48) | ELANEACHEPPARGPPARA | |
| SCHEMBL23996159 | 0.82 | KMT2A (0.57) | KMT2APDGFRBPDGFRAACHETDP1 | |
| SCHEMBL28040668 | 0.82 | KMT2A (0.56) | KMT2APDGFRBPDGFRAACHETDP1 | |
| SCHEMBL28121828 | 0.81 | KMT2A (0.58) | KMT2AAKR1C3RAB9A | |
| SCHEMBL22924623 | 0.80 | PPARA (0.55) | ELANEACHEPPARGPPARA | |
| SCHEMBL5085655 | 0.80 | ELANE (0.44) | ELANEACHEPPARGPPARA | |
| SCHEMBL16959817 | 0.79 | ELANE (0.49) | KMT2AELANEACHEPPARGPPARA | |
| SCHEMBL28122438 | 0.79 | KMT2A (0.60) | KMT2APDGFRBPDGFRATDP1MEN1 | |
| SCHEMBL28080644 | 0.79 | KMT2A (0.51) | KMT2ATDP1PPARGPPARAAKR1C3 | |
| SCHEMBL11771781 | 0.78 | ELANE (0.67) | KMT2AELANETDP1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103224474-B | The synthesis of tetracycline and the like | 哈佛大学校长及研究员协会 | 2016-08-03 | — | — | CN | disclosed |
| CN-103214409-B | The synthesis of tsiklomitsin and analogue thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-21 | — | — | CN | disclosed |
| CN-103224474-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-31 | — | — | CN | disclosed |
| CN-103214409-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-24 | — | — | CN | disclosed |
| CN-101027279-B | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-03-27 | — | — | CN | disclosed |
| CN-101027279-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE (US) | 2007-08-29 | — | — | CN | disclosed |