Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23996159 | 0.88 | KMT2A (0.57) | KMT2ATDP1PDGFRBPDGFRAACHE | |
| SCHEMBL28121828 | 0.86 | KMT2A (0.58) | KMT2A | |
| SCHEMBL1050111 | 0.85 | KMT2A (0.73) | KMT2ATDP1PDGFRBPDGFRAFFAR1 | |
| SCHEMBL28122438 | 0.84 | KMT2A (0.60) | KMT2ATDP1PDGFRBPDGFRAFFAR1 | |
| Hydrogen Sulfide SCHEMBL27894387 | 0.83 | KMT2A (0.71) | KMT2ATDP1PDGFRBPDGFRAFFAR1 | |
| Hydrogen Sulfide SCHEMBL28066373 | 0.83 | KMT2A (0.71) | KMT2ATDP1PDGFRBPDGFRAFFAR1 | |
| SCHEMBL27537713 | 0.83 | KMT2A (0.71) | KMT2ATDP1PDGFRBPDGFRAFFAR1 | |
| SCHEMBL10882168 | 0.83 | KMT2A (0.71) | KMT2ATDP1PDGFRBPDGFRAFFAR1 | |
| SCHEMBL11433784 | 0.83 | KMT2A (0.55) | KMT2ATDP1PDGFRBPDGFRAFFAR1 | |
| SCHEMBL27680586 | 0.82 | KMT2A (0.51) | KMT2ATDP1PDGFRBPDGFRAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214409-B | The synthesis of tsiklomitsin and analogue thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-21 | — | — | CN | disclosed |