SCHEMBL27680592

SCHEMBL27680592

ClOCl.[SeH2].c1ccc(Cn2cccn2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
GAA P10253 1/20 0.54
HTT P42858 1/20 0.54
CYP19A1 P11511 4/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
NOS3 P29474 1/20 0.49
NOS1 P29475 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
TSHR P16473 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.43
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Selenium SCHEMBL10541726 0.96 MAPT (0.54) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL324202 0.92 MAPT (0.61) MAPTGAAHTTCYP19A1HDAC1
Hydrochloric Acid SCHEMBL15366234 0.90 MAPT (0.59) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL28064719 0.84 CA12 (0.59) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL3519967 0.80 MAPT (0.54) MAPTGAAHTTCYP19A1HDAC6
SCHEMBL3433732 0.79 GAA (0.59) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL22181781 0.79 CA12 (0.71) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL14256403 0.79 HTT (0.68) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL15081591 0.77 HTT (0.61) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL28120381 0.77 HTT (0.57) MAPTGAAHTTCYP19A1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-86107767-A NOVEL ORGANIC SELENIUM COMPOUNDS 1987-08-05 CN disclosed