SCHEMBL324202

SCHEMBL324202

c1ccc(Cn2cccn2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.61
GAA P10253 1/20 0.61
HTT P42858 1/20 0.60
CYP19A1 P11511 6/20 0.57
HDAC1 Q13547 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
NOS3 P29474 1/20 0.54
NOS1 P29475 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
TSHR P16473 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
CYP1A2 P05177 1/20 0.47
POLB P06746 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15366234 0.98 MAPT (0.59) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL27680592 0.92 MAPT (0.54) MAPTGAAHTTCYP19A1HDAC1
Selenium SCHEMBL10541726 0.92 MAPT (0.54) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL28064719 0.91 CA12 (0.59) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL3433732 0.85 GAA (0.59) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL22181781 0.85 CA12 (0.71) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL14256403 0.85 HTT (0.68) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL15081591 0.84 HTT (0.61) MAPTGAAHTTCYP19A1HDAC1
SCHEMBL3519967 0.83 MAPT (0.54) MAPTGAAHTTCYP19A1HDAC6
SCHEMBL28120381 0.83 HTT (0.57) MAPTGAAHTTCYP19A1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 619 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026047173-A1 PROCESS FOR PREPARING SUSTAINABLE JET FUELS OR DIESEL FUELS; AND PRECURSORS THEREOF Terra Mater BV (BE) 2026-03-05 WO claimed
EP-4622945-A1 OLIGOMERISATION OF ALCOHOLS Terra Mater BV (BE) 2025-10-01 EP claimed
WO-2024110575-A1 OLIGOMERISATION OF ALCOHOLS Terra Mater BV (BE) 2024-05-30 WO claimed
US-20240043809-A1 Intestinal organoid co-culture systems and methods for treating or preventing a disease or disorder associated with immune response-mediated tissue injury NEW YORK UNIVERSITY 2024-02-08 US claimed
CN-115894373-A N-substituted benzylpyrazole derivatives as beta 2 Use of allosteric modulators, antagonists and agonists of the adrenergic receptor 常州大学 2023-04-04 CN claimed
CN-112778202-B Benzyl pyrazole ionic liquid compound and preparation method and application thereof 河南大学 2022-07-05 CN claimed
EP-3288942-B1 RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2021-10-27 EP claimed
US-11084826-B2 RSV antiviral pyrazolo- and triazolo-pyrimidine compounds Janssen Sciences Ireland Unlimited Company (IE) 2021-08-10 US claimed
US-20210139857-A1 Intestinal organoid co-culture systems and methods for treating or preventing a disease or disorder associated with immune response-mediated tissue injury NEW YORK UNIVERSITY 2021-05-13 US claimed
CN-112778202-A Benzyl pyrazole ionic liquid compound and preparation method and application thereof 河南大学 2021-05-11 CN claimed
US-20050261206-A1 Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof KISSEI PHARMACEUTICAL CO., LTD. 2005-11-24 US claimed
WO-2005020897-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION DENDREON CORPORATION (US) 2005-03-10 WO claimed
US-20040147729-A1 Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof KISSEI PHARMACEUTICAL CO., LTD. 2004-07-29 US claimed
EP-1213296-B1 GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF KISSEI PHARMACEUTICAL (JP) 2004-04-14 EP claimed
EP-1213296-A1 GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF Kissei Pharmaceutical Co., Ltd. (JP) 2002-06-12 EP claimed
EP-0751944-B1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL IND LTD (JP) 2000-12-20 EP claimed
US-5955481-A Pyridine type thiazolidines NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-21 US claimed
EP-0751944-A1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-01-08 EP claimed
WO-1995026347-A1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1995-10-05 WO claimed
US-5409893-A Administering with platinum complexes BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) 1995-04-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11084826-B2 RSV antiviral pyrazolo- and triazolo-pyrimidine compounds ZC3HAV1, MAVS, TYMP MAPT 3325/4885GAA 2343/4885HTT 4378/4885
US-20040147729-A1 Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof SLC5A1, SLC5A2, UGGT1 MAPT 2024/4885GAA 300/4885HTT 1455/4885
US-20050261206-A1 Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof SLC5A1, SLC5A2, UGGT1 MAPT 1571/4885GAA 302/4885HTT 1321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.