Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27499876 | 1.00 | PAOX (0.34) | PAOXGABRR1ALDH1A1FFAR3LCK | |
| SCHEMBL1548232 | 0.83 | — | — | |
| SCHEMBL27752981 | 0.80 | — | — | |
| Acetic Acid SCHEMBL7917433 | 0.74 | ALDH1A1 (0.38) | PAOXALDH1A1 | |
| Acetic Acid SCHEMBL28979999 | 0.73 | CA12 (0.53) | PAOXALDH1A1ALOX15HSD17B10 | |
| Acetic Acid SCHEMBL10933237 | 0.72 | FFAR3 (0.41) | PAOXGABRR1ALDH1A1FFAR3LCK | |
| Acetic Acid SCHEMBL9100273 | 0.72 | CA12 (0.59) | PAOXALDH1A1FFAR3LCKFYN | |
| Acetic Acid SCHEMBL3657736 | 0.72 | CA12 (0.59) | PAOXALDH1A1FFAR3LCKFYN | |
| Acetic Acid SCHEMBL18288 | 0.72 | CA12 (0.59) | PAOXALDH1A1FFAR3LCKFYN | |
| Acetic Acid SCHEMBL1565417 | 0.72 | CA12 (0.59) | PAOXALDH1A1FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039723-B | Personal care compositions comprising visible beads, cationic polymer, and surfactant | PROCTER & GAMBLE | 2013-06-19 | — | — | CN | disclosed |
| CN-101994105-A | Preparation of polymer-containing substrates for metallization | ROHM & HAAS ELECT MAT | 2011-03-30 | — | — | CN | disclosed |
| CN-101039723-A | Personal care compositions comprising visible beads, cationic polymer, and surfactant | PROCTER & GAMBLE (US) | 2007-09-19 | — | — | CN | disclosed |