Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680894 | 1.00 | KMT2A (0.51) | KMT2ATSHRSMN1; SMN2CTSGCTRB1 | |
| SCHEMBL7899184 | 0.91 | KMT2A (0.49) | KMT2A | |
| SCHEMBL1405655 | 0.89 | KMT2A (0.53) | KMT2ATSHRSMN1; SMN2MMP12 | |
| SCHEMBL9555874 | 0.89 | KMT2A (0.53) | KMT2ATSHRSMN1; SMN2MMP12 | |
| SCHEMBL9574058 | 0.87 | CTSK (0.46) | KMT2ATSHRSMN1; SMN2CTSGCTRB1 | |
| SCHEMBL4831220 | 0.87 | CTSK (0.46) | KMT2ATSHRSMN1; SMN2CTSGCTRB1 | |
| SCHEMBL28325731 | 0.85 | KMT2A (0.74) | KMT2ATSHRSMN1; SMN2CTSGCTRB1 | |
| SCHEMBL7506768 | 0.84 | KMT2A (0.54) | KMT2AMEN1ALDH1A1ABCB1 | |
| SCHEMBL9755831 | 0.84 | KMT2A (0.54) | KMT2AMEN1ALDH1A1ABCB1 | |
| SCHEMBL1856103 | 0.84 | CA1 (0.51) | KMT2ATSHRSMN1; SMN2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100467479-C | Phosphine-phosphoramidite ligand, its preparation method and uses | DALIAN CHEMICAL PHYSICS INST (CN) | 2009-03-11 | — | — | CN | disclosed |
| CN-1951945-A | Phosphine-phosphoramidite ligand, its preparation method and uses | DALIAN CHEMICAL PHYSICS INST (CN) | 2007-04-25 | — | — | CN | disclosed |
| CN-1951946-A | Chiral monodentate phosphite ligands, its preparation method and uses | DALIAN CHEMICAL PHYSICS INST (CN) | 2007-04-25 | — | — | CN | disclosed |