Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPEPLD | Q6IQ20 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117364 | 0.89 | PIK3CA (0.59) | NAPEPLDPIK3CA | |
| SCHEMBL3112884 | 0.88 | PIK3CA (0.52) | NAPEPLDHTTLMNAPOLBHSD17B10 | |
| SCHEMBL3103448 | 0.79 | NAPEPLD (0.49) | NAPEPLDHTTLMNAPOLBHSD17B10 | |
| SCHEMBL3102408 | 0.78 | NAPEPLD (0.56) | NAPEPLDHTTPOLBPIK3CAKDM4E | |
| SCHEMBL11926388 | 0.77 | NAPEPLD (0.55) | NAPEPLDHTTPIK3CAALDH1A1 | |
| SCHEMBL3106073 | 0.77 | PIK3CA (0.62) | NAPEPLDPIK3CA | |
| SCHEMBL3103084 | 0.77 | PIK3CA (0.52) | NAPEPLDHTTLMNAPOLBHSD17B10 | |
| SCHEMBL11926389 | 0.76 | NAPEPLD (0.53) | NAPEPLDPIK3CAKDM4E | |
| SCHEMBL11926395 | 0.76 | NAPEPLD (0.53) | NAPEPLDPIK3CAMAPK1 | |
| SCHEMBL3105942 | 0.75 | MAPK1 (0.51) | NAPEPLDHTTLMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023063-A | Azine-carboxamides as anti-cancer agents | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | claimed |