Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27854166 | 1.00 | PTPN1 (0.55) | PTPN1HDAC8MAPTKDM4EALDH1A1 | |
| SCHEMBL4837953 | 0.85 | MAPT (0.53) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL928146 | 0.85 | LMNA (0.52) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9542638 | 0.85 | KDM4E (0.48) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9542646 | 0.85 | KDM4E (0.48) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30681423 | 0.81 | PTPN1 (0.46) | PTPN1LMNA | |
| SCHEMBL22673082 | 0.80 | LMNA (0.44) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL705456 | 0.80 | ACE (0.55) | — | |
| SCHEMBL927332 | 0.80 | ACE (0.55) | — | |
| SCHEMBL29545684 | 0.80 | ACE (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950340-A | LXR receptor modulators | FOURNIER LAB SA (FR) | 2007-04-18 | — | — | CN | disclosed |