Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.55 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 2/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30369932 | 1.00 | LCK (0.56) | LCKBTKPI4K2ABCAT2CHEK1 | |
| SCHEMBL28136345 | 1.00 | LCK (0.56) | LCKBTKPI4K2ABCAT2CHEK1 | |
| SCHEMBL6997464 | 0.88 | PI4K2A (0.55) | LCKBTKPI4K2ABCAT2CHEK1 | |
| SCHEMBL28264516 | 0.88 | PI4K2A (0.55) | LCKBTKPI4K2ABCAT2CHEK1 | |
| SCHEMBL29479384 | 0.87 | KDM4E (0.53) | LCKBTKPI4K2AMPOGHSR | |
| SCHEMBL16720498 | 0.87 | KDM4E (0.53) | LCKBTKPI4K2AMPOGHSR | |
| SCHEMBL3425920 | 0.83 | LCK (0.52) | LCKBTKPI4K2AIKBKBCHUK | |
| SCHEMBL29437284 | 0.82 | PI4K2A (0.55) | LCKBTKPI4K2AIKBKBCHUK | |
| SCHEMBL30841297 | 0.82 | SLC6A3 (0.66) | LCKBTKGHSRCCNCCDK8 | |
| SCHEMBL28555350 | 0.80 | SLC6A2 (0.49) | LCKBTKPI4K2AGHSRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605759-A | 1-benzenesulfonyl-1H-indole derivatives as inhibitors of CCR9 activity | NOVARTIS AG (CH) | 2009-12-16 | — | — | CN | disclosed |
| CN-101035527-A | Methods of treating a disorder | ELIXIR PHARMACEUTICALS INC (US) | 2007-09-12 | — | — | CN | disclosed |