Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27682129 | 0.83 | LRRK2 (0.47) | KCNH2L3MBTL1KDM4EALDH1A1LMNA | |
| Benzene SCHEMBL27682163 | 0.81 | KCNH2 (0.41) | KCNH2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL13354443 | 0.79 | LRRK2 (0.49) | KCNH2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL13086425 | 0.75 | PIM1 (0.42) | KCNH2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL30635496 | 0.74 | PIK3CD (0.47) | KCNH2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL18487593 | 0.74 | L3MBTL1 (0.65) | KCNH2L3MBTL1KDM4EALDH1A1LMNA | |
| Benzene SCHEMBL27662532 | 0.73 | PIK3CD (0.44) | KCNH2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL12369720 | 0.72 | L3MBTL1 (0.65) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| Benzene SCHEMBL27682259 | 0.72 | CREBBP (0.46) | KCNH2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL21744554 | 0.71 | MKNK1 (0.55) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | claimed |
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | disclosed |