Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5116230 | 0.90 | MAPT (0.35) | SIGMAR1GCGRPSEN1PSEN2APH1B | |
| SCHEMBL27662807 | 0.89 | DPP4 (0.34) | SIGMAR1 | |
| SCHEMBL4772589 | 0.89 | MAPT (0.33) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27662580 | 0.88 | MAPT (0.36) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5367889 | 0.87 | PSEN1 (0.34) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27682184 | 0.84 | KDM4E (0.36) | SIGMAR1GCGRPSEN1PSEN2APH1B | |
| SCHEMBL4772587 | 0.83 | MAPT (0.33) | MAPTTSHRNPSR1RECQLMEN1 | |
| SCHEMBL27662703 | 0.83 | PRKAA2 (0.36) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5370268 | 0.82 | CYP11B1 (0.37) | SIGMAR1GCGRALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL27682179 | 0.82 | PDE10A (0.37) | SIGMAR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | disclosed |