Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.66 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257411 | 0.88 | FFAR1 (0.66) | FFAR1S1PR1LMNAL3MBTL1S1PR3 | |
| SCHEMBL8767174 | 0.87 | FFAR1 (0.79) | FFAR1S1PR1LMNAL3MBTL1S1PR3 | |
| SCHEMBL11311575 | 0.83 | S1PR1 (0.68) | FFAR1S1PR1LMNAL3MBTL1S1PR3 | |
| SCHEMBL11309024 | 0.83 | S1PR1 (0.68) | FFAR1S1PR1LMNAL3MBTL1S1PR3 | |
| SCHEMBL25175626 | 0.83 | S1PR1 (0.68) | FFAR1S1PR1LMNAL3MBTL1S1PR3 | |
| SCHEMBL7750520 | 0.82 | PLA2G4B (0.60) | FFAR1LMNAL3MBTL1PPARASMN1; SMN2 | |
| SCHEMBL7257905 | 0.82 | FFAR1 (0.71) | FFAR1LMNAL3MBTL1PPARAFFAR4 | |
| SCHEMBL4898898 | 0.81 | FFAR1 (0.68) | FFAR1S1PR1LMNAL3MBTL1S1PR3 | |
| SCHEMBL7999557 | 0.81 | FFAR1 (0.65) | FFAR1S1PR1LMNAL3MBTL1S1PR3 | |
| SCHEMBL7565477 | 0.81 | FFAR1 (0.67) | FFAR1S1PR1LMNAL3MBTL1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993326-A | Heterocyclic acetophenone potentiators of metabotropic glutamate receptors | MERCK & CO INC (US) | 2007-07-04 | — | — | CN | disclosed |