Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999557 | 0.87 | FFAR1 (0.65) | FFAR1LMNAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL1532487 | 0.85 | FFAR1 (0.72) | FFAR1LMNAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL20799670 | 0.85 | FFAR1 (0.65) | FFAR1LMNAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL2891962 | 0.84 | FFAR1 (0.58) | FFAR1LMNAL3MBTL1LTA4HPPARG | |
| SCHEMBL2628225 | 0.84 | FFAR1 (0.66) | FFAR1LMNAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL16686916 | 0.84 | LMNA (0.69) | FFAR1LMNAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL2628227 | 0.84 | FFAR1 (0.66) | FFAR1LMNAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL27619975 | 0.84 | SMN1; SMN2 (0.69) | FFAR1LMNAPPARAFFAR4HDAC3 | |
| SCHEMBL28934486 | 0.84 | LTA4H (0.65) | FFAR1LMNALTA4HEPHX2PPARA | |
| SCHEMBL31448501 | 0.84 | PPARA (0.65) | FFAR1LMNAL3MBTL1PPARAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689845-B1 | Conjugates of methyltrithio antitumor agents and intermediates for their synthesis | AMERICAN CYANAMID CO (US) | 2002-09-04 | — | — | EP | disclosed |
| US-5877296-A | REACTING DISULFIDE ANALOGS OF CALICHEAMICIN FAMILY WITH A CARRIER SUCH AS PROTEIN, PEPTIDE, MONO AND POLYCLONAL ANTIBODIES, THEIR ANTIGEN-RECOGNIZING FRAGMENTS AND CHEMICALLY OR GENETICALLY ENGINEERED COUNTERPARTS | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| US-5773001-A | ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1998-06-30 | — | — | US | disclosed |
| US-5767285-A | USEFUL FOR CONSTRUCTING DRUG CONJUGATES; ANTIBIOTIC ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1998-06-16 | — | — | US | disclosed |
| US-5739116-A | DISULFIDE DERIVATIVE OF CALICHEAMICIN FAMILY; ANTITUMOR ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0689845-A2 | Conjugates of methyltrithio antitumor agents and intermediates for their synthesis | AMERICAN CYANAMID COMPANY (US) | 1996-01-03 | — | — | EP | disclosed |