Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | KHK | P50053 | 1/20 | 0.49 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389631 | 0.90 | ALDH1A1 (0.52) | KDM1AMAOBMAOAGBA1KHK | |
| SCHEMBL17064950 | 0.87 | ALDH1A1 (0.54) | KDM1AMAOBMAOAMAN1B1ALDH1A1 | |
| SCHEMBL6224721 | 0.83 | KDM1A (0.50) | KDM1AMAOBMAOAGBA1MAN1B1 | |
| SCHEMBL22694642 | 0.81 | KDM1A (0.53) | KDM1AMAOBMAOAGBA1MAN1B1 | |
| SCHEMBL21266856 | 0.81 | KDM1A (0.53) | KDM1AMAOBMAOAGBA1MAN1B1 | |
| SCHEMBL24767234 | 0.81 | KDM1A (0.53) | KDM1AMAOBMAOAGBA1MAN1B1 | |
| SCHEMBL22404280 | 0.81 | KDM1A (0.53) | KDM1AMAOBMAOAGBA1MAN1B1 | |
| SCHEMBL3628527 | 0.81 | GBA1 (0.53) | KDM1AMAOBMAOAGBA1KHK | |
| Hydrochloric Acid SCHEMBL7093141 | 0.81 | BRD4 (0.43) | KDM1AMAOBMAOAKHKITGB3 | |
| Methane SCHEMBL3590620 | 0.80 | GBA1 (0.52) | KDM1AMAOBMAOAGBA1KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101080388-B | Piperidinesulfonylureas and -thioureas, their preparation, their use and pharmaceutical compositions comprising them | SANOFI AVENTIS DEUTSCHLAND | 2010-12-22 | — | — | CN | disclosed |
| CN-101080388-A | Piperidinesulfonylureas and -thioureas, their preparation, their use and pharmaceutical compositions comprising them | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-11-28 | — | — | CN | disclosed |