Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 2/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682985 | 0.90 | SLC6A4 (0.45) | SLC6A4SLC6A2HTR2AHTR2CPHGDH | |
| SCHEMBL27687228 | 0.87 | SLC6A2 (0.57) | SLC6A4SLC6A2HTR2AHTR2CPHGDH | |
| SCHEMBL2073883 | 0.81 | SLC6A4 (0.72) | SLC6A4SLC6A2HTR2A | |
| SCHEMBL27719828 | 0.76 | ALOX5 (0.49) | SLC6A4SLC6A2 | |
| SCHEMBL28761763 | 0.75 | SLC6A2 (0.47) | SLC6A4SLC6A2OXER1 | |
| SCHEMBL4082247 | 0.75 | SLC6A4 (0.74) | SLC6A4SLC6A2 | |
| SCHEMBL4081911 | 0.75 | SLC6A4 (0.74) | SLC6A4SLC6A2 | |
| SCHEMBL27663360 | 0.74 | HDAC8 (0.51) | SLC6A4SLC6A2PHGDH | |
| SCHEMBL28765088 | 0.73 | SLC6A2 (0.43) | SLC6A4SLC6A2 | |
| SCHEMBL28761093 | 0.73 | SLC6A2 (0.43) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993321-A | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors | HOFFMANN LA ROCHE (CH) | 2007-07-04 | — | — | CN | disclosed |