Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685287 | 0.83 | EGFR (0.52) | VCPGSK3BALOX5MAP4K4MAPK1 | |
| SCHEMBL27685418 | 0.78 | KMT2A (0.51) | MEN1KMT2AAURKA | |
| SCHEMBL26094287 | 0.78 | SCN2A (0.73) | MAPK1SCN2APOLBCYP19A1 | |
| SCHEMBL27685301 | 0.73 | SCN2A (0.48) | MAPTMEN1KMT2ASCN2AHTT | |
| SCHEMBL11156115 | 0.72 | GSK3B (0.53) | VCPGSK3BMAPTMEN1KMT2A | |
| SCHEMBL25243020 | 0.70 | MEN1 (0.47) | MAPTMEN1KMT2ACYP3A4GAA | |
| SCHEMBL14465944 | 0.69 | VCP (1.00) | VCPALOX5 | |
| SCHEMBL25286380 | 0.69 | SCN2A (0.60) | GSK3BMAPTCYP3A4ALOX15SCN2A | |
| SCHEMBL8383701 | 0.68 | COMT (0.65) | MEN1KMT2ATSHRMAPK1SCN2A | |
| SCHEMBL1180501 | 0.68 | SCN2A (0.64) | GSK3BSCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101044125-A | Heterocyclic compounds and methods of use | TARGEGEN INC (US) | 2007-09-26 | — | — | CN | disclosed |