⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031070 | 1.00 | — | — | |
| SCHEMBL27705009 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1686550 | 0.97 | — | — | |
| SCHEMBL31135591 | 0.81 | — | — | |
| SCHEMBL5254652 | 0.78 | — | — | |
| SCHEMBL379022 | 0.78 | — | — | |
| SCHEMBL23336211 | 0.74 | — | — | |
| SCHEMBL27676145 | 0.74 | — | — | |
| SCHEMBL134555 | 0.73 | — | — | |
| SCHEMBL6597286 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103073460-B | Be applicable to treat the aromatic substance that the arylsulfonyl ylmethyl of the disease responded for the adjustment of dopamine D 3 receptor or aryl sulfonic acid amides replace | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-09-09 | — | — | CN | disclosed |
| CN-103073460-A | Arylsulfonylmethyl or arylsulfonamide substituted aromatic compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor | ABBOTT GMBH & CO KG | 2013-05-01 | — | — | CN | disclosed |
| CN-101421243-A | Aryloxyethylamine compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor | ABBOTT GMBH & CO KG (DE) | 2009-04-29 | — | — | CN | disclosed |
| CN-101068801-A | Arylsulfonylmethyl or arylsulfonamide substituted aromatic compounds suitable for the treatment of disorders which respond to modulation of the dopamine D3 receptor | ABBOTT GMBH & CO KG (DE) | 2007-11-07 | — | — | CN | disclosed |
| CN-101039900-A | 6-amino(aza)indane compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor | ABBOTT GMBH & CO KG (DE) | 2007-09-19 | — | — | CN | disclosed |