SCHEMBL379022

SCHEMBL379022

CCCC(F)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5254652 1.00
SCHEMBL23336211 0.85
SCHEMBL11569345 0.81 MAPT (0.67)
SCHEMBL11412696 0.81 MAPT (0.67)
SCHEMBL27705009 0.78
SCHEMBL27685993 0.78
SCHEMBL1031070 0.78
SCHEMBL25364160 0.77
Potassium Ion SCHEMBL25367311 0.77
SCHEMBL2280835 0.77 MAPT (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408450-A1 A NOVEL ALPHA-(N-SULFONAMIDO)ACETAMIDE COMPOUND AS AN INHIBITOR OF BETA AMYLOID PEPTIDE PRODUCTION Bristol-Myers Squibb Company (US) 2012-01-25 EP claimed
WO-2010107435-A1 A NOVEL ALPHA-(N-SULFONAMIDO)ACETAMIDE COMPOUND AS AN INHIBITOR OF BETA AMYLOID PEPTIDE PRODUCTION BRISTOL-MYERS SQUIBB COMPANY (US) 2010-09-23 WO claimed
WO-1998027051-A9 CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES 1998-11-12 WO claimed
WO-1998027051-A2 CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES THE SCRIPPS RESEARCH INSTITUTE (US) 1998-06-25 WO claimed
WO-2025262036-A1 METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION RNASSIST LTD (GB) 2025-12-26 WO disclosed
EP-3827241-B1 DISSOCIATION OF BIOLOGICAL SAMPLES GOLDSBOROUGH ANDREW SIMON (FR) 2024-03-13 EP disclosed
US-20240027309-A1 SIMPLE FIXATION AND STABILISATION RNASSIST LTD (GB) 2024-01-25 US disclosed
US-20230220313-A1 COMPOSITION AND METHOD FOR INACTIVATING A VIRUS RNASSIST LTD. (GB) 2023-07-13 US disclosed
EP-4133062-A1 COMPOSITION AND METHOD FOR INACTIVATING A VIRUS Rnassist Limited (GB) 2023-02-15 EP disclosed
US-20210231538-A1 DISSOCIATION OF BIOLOGICAL SAMPLES GOLDSBOROUGH ANDREW SIMON (FR) 2021-07-29 US disclosed
EP-3827241-A1 DISSOCIATION OF BIOLOGICAL SAMPLES Goldsborough, Andrew Simon (FR) 2021-06-02 EP disclosed
EP-3788873-A1 SAMPLE FIXATION AND STABILISATION Goldsborough, Andrew Simon (FR) 2021-03-10 EP disclosed
US-7759397-B2 6-amino(aza)indane compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor ABBOTT GMBH & CO. KG (DE) 2010-07-20 US disclosed
US-20090143383-A1 ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR ABBOTT GMBH & CO. KG (DE) 2009-06-04 US disclosed
US-20090048326-A1 Azabicycloheptyl compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2009-02-19 US disclosed
EP-2013179-A1 ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR Abbott GmbH & Co. KG (DE) 2009-01-14 EP disclosed
US-20090012074-A1 Arylsulfonylmethyl or arylsulfonamide substituted aromatic compounds suitable for treating disorders that respond to modulation of the Dopamine D3 receptor ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2009-01-08 US disclosed
US-20080318996-A1 6-Amino(Aza)Indane Compounds Suitable for Treating Disorders that Respond to Modulation of the Dopamine D3 Receptor ABBOTT GMBH & CO.KG A CORPORATION 2008-12-25 US disclosed
US-20080096934-A1 Aminoethylaromatic Compounds Suitable For Treating Disorders That Respond To Modulation Of The Dopamine D3 Receptor ABBOTT GMBH & CO. KG (DE) 2008-04-24 US disclosed
WO-2007118859-A1 ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR ABBOTT GMBH & CO. KG (DE) 2007-10-25 WO disclosed