Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | POLG | P54098 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144357 | 0.82 | POLG (0.44) | FGFR1SLC22A6POLGPOLBLMNA | |
| SCHEMBL1629582 | 0.82 | FGFR1 (0.44) | FGFR1SLC22A6POLGPOLBLMNA | |
| SCHEMBL76047 | 0.80 | POLG (0.47) | FGFR1SLC22A6POLGPOLBP2RY2 | |
| SCHEMBL10496372 | 0.80 | POLG (0.47) | FGFR1SLC22A6POLGPOLBP2RY2 | |
| SCHEMBL26123976 | 0.79 | POLG (0.47) | FGFR1SLC22A6POLGPOLBP2RY2 | |
| SCHEMBL28004770 | 0.77 | FGFR1 (0.40) | FGFR1SLC22A6POLGPOLBLMNA | |
| SCHEMBL28199180 | 0.77 | FGFR1 (0.37) | FGFR1SLC22A6POLGPOLBP2RY2 | |
| SCHEMBL5356639 | 0.77 | FGFR1 (0.39) | FGFR1SLC22A6POLGPOLBLMNA | |
| SCHEMBL24512713 | 0.76 | FGFR1 (0.36) | FGFR1SLC22A6POLGPOLBP2RY2 | |
| SCHEMBL27480335 | 0.74 | LMNA (0.53) | POLBLMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101132795-A | Compounds useful in the treatment of HIV | MEDIVIR AB (SE) | 2008-02-27 | — | — | CN | disclosed |