Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768992 | 1.00 | MAPT (0.40) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL4084569 | 0.85 | MAPT (0.39) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL4084574 | 0.85 | MAPT (0.39) | MAPTNPC1RAB9AKMT2APSMD14 | |
| Bromide SCHEMBL3175293 | 0.84 | MAPT (0.38) | MAPTNPC1RAB9AKMT2APSMD14 | |
| Bromide SCHEMBL3175284 | 0.84 | MAPT (0.38) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL2769671 | 0.83 | KDR (0.38) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2769674 | 0.83 | KDR (0.38) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2770403 | 0.82 | INSR (0.39) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL2770406 | 0.82 | INSR (0.39) | MAPTNPC1RAB9AKMT2APSMD14 | |
| Bromide SCHEMBL2771290 | 0.82 | INSR (0.38) | MAPTNPC1RAB9AKMT2APSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1825883-B1 | Agents for coloring keratin fibers | PROCTER & GAMBLE (US) | 2010-04-14 | — | — | EP | disclosed |
| US-7658770-B2 | Agents for coloring keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2010-02-09 | — | — | US | disclosed |
| US-20090165221-A1 | Agents for Coloring Keratin Fibers | WELLA OPERATIONS US, LLC | 2009-07-02 | — | — | US | disclosed |
| US-7513916-B2 | Agents for coloring keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-07 | — | — | US | disclosed |
| US-20070199160-A1 | Agents for coloring keratin fibers | THE PROCTER & GAMBLE COMPANY | 2007-08-30 | — | — | US | disclosed |
| WO-2007097930-A1 | AGENTS FOR COLORING KERATIN FIBERS | THE PROCTER & GAMBLE COMPANY (US) | 2007-08-30 | — | — | WO | disclosed |
| EP-1825883-A1 | Agents for coloring keratin fibers | Wella Aktiengesellschaft (DE) | 2007-08-29 | — | — | EP | disclosed |
| EP-1820537-A1 | Agents for coloring keratin fibers | Wella Aktiengesellschaft (DE) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090165221-A1 | Agents for Coloring Keratin Fibers | KRT18, IK, KRTCAP2 | MAPT 781/4885NPC1 4249/4885RAB9A 3182/4885 |
| US-20070199160-A1 | Agents for coloring keratin fibers | KRT18, IK, KRTCAP2 | MAPT 781/4885NPC1 4249/4885RAB9A 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.