Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14805006 | 0.82 | EPHX2 (0.62) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2769319 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2768541 | 0.79 | MAPT (0.56) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2772189 | 0.77 | HIF1A (0.58) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2771566 | 0.77 | ALDH1A1 (0.50) | PPIAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2771187 | 0.77 | SMN1; SMN2 (0.61) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2768326 | 0.77 | HIF1A (0.60) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2768846 | 0.76 | HIF1A (0.64) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2768684 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2768457 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | GRUENENTHAL GMBH (DE) | 2008-07-24 | — | — | US | claimed |
| US-7696238-B2 | Substituted benzo[d]isoxazol-3-yl amine compounds as analgesics | GRUENENTHAL GMBH (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | GRUENENTHAL GMBH (DE) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | KCNQ1, KCNQ2, KCNQ3 | PPIA 3661/4885ALDH1A1 1965/4885MAPT 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.