Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834193 | 0.91 | BAZ2B (0.68) | BAZ2BRAB9AMAPK14NPC1KDM4E | |
| SCHEMBL21765666 | 0.81 | RAB9A (0.71) | RAB9APOLBNPC1KDM4EMAPT | |
| SCHEMBL15190881 | 0.81 | BAZ2B (0.60) | BAZ2BRAB9AMAPK14NPC1MKNK1 | |
| SCHEMBL1091777 | 0.80 | BAZ2B (0.82) | BAZ2BRAB9AMAPK14NPC1CASP1 | |
| SCHEMBL1091505 | 0.79 | BAZ2B (0.56) | BAZ2BRAB9AMAPK14NPC1MAPT | |
| SCHEMBL1091597 | 0.77 | BAZ2B (0.60) | BAZ2BRAB9AMAPK14NPC1MKNK1 | |
| SCHEMBL21505098 | 0.77 | BAZ2B (0.60) | BAZ2BRAB9AMAPK14POLBNPC1 | |
| SCHEMBL29975245 | 0.76 | NPC1 (0.64) | RAB9APOLBNPC1KDM4E | |
| SCHEMBL28366098 | 0.76 | NPC1 (0.64) | RAB9APOLBNPC1KDM4E | |
| SCHEMBL10751140 | 0.76 | BAZ2B (0.55) | BAZ2BRAB9AMAPK14NPC1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85101925-A | Prepare the method that salt is allowed in heterogeneous ring compound and pharmacy thereof | — | 1987-01-24 | — | — | CN | disclosed |