Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27690178 | 0.95 | TDP1 (0.43) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL9832787 | 0.73 | CYP1A2 (0.45) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL9831613 | 0.72 | PGR (0.48) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL27671304 | 0.69 | TDP1 (0.36) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL9832576 | 0.68 | TDP1 (0.48) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL27690192 | 0.68 | MAPT (0.35) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL27671281 | 0.67 | TDP1 (0.36) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL2487418 | 0.66 | TDP1 (0.49) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL12279934 | 0.66 | TDP1 (0.55) | TDP1CYP1A2CYP2C9CYP2C19MPI | |
| SCHEMBL2248587 | 0.65 | CYP1A2 (0.45) | TDP1CYP1A2CYP2C9CYP2C19MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85103724-B | Process for preparing pyrrolobenzimidazoles | 曼海姆伯灵格股份公司 | 1988-07-06 | — | — | CN | disclosed |
| CN-85103724-A | The method for preparing novel pyrrolo-benzoglyoxaline | — | 1986-07-02 | — | — | CN | disclosed |