Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.79 |
| ▸ | RAB9A | P51151 | 6/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865105 | 0.93 | RAB9A (0.69) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL2866102 | 0.91 | RAB9A (0.66) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL2865869 | 0.90 | KMT2A (0.65) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL2866086 | 0.90 | GAA (0.65) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL4362238 | 0.88 | RAB9A (0.62) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL2862550 | 0.88 | RAB9A (0.62) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL7860721 | 0.86 | RAB9A (0.73) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL4366508 | 0.83 | KMT2A (0.60) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL2862776 | 0.82 | KMT2A (0.55) | GAARAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL4370761 | 0.81 | KMT2A (0.54) | GAARAB9AKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087755-A | Substituted arylacylthioureas and related compounds; inhibitors of viral replication | ACHILLION PHARMACEUTICALS INC (US) | 2007-12-12 | — | — | CN | claimed |